Development of strain libraries, media and bioreactor processes for BSL1 and 2 strains
Lead set-up,maintenance and operationof bioprocess equipmentincluding: Fermenters, nano filtration, centrifugation, spectrophotometer, HPLC, benchtop shake flasks experiments and drying technologies including spray drying and lyophilization.
Performance of laboratory experiments to understand the fundamental mechanismassociated with scale up and scale down of bacteria metabolite processes
Establish processparameters, critical controlparameters, process locks associated with the production of specific fermentation primary/secondary metabolites
Develop novel technologies for the formulation, preservation, and analysisof novel microbial products.
Conduct small-scale fermentation and freeze-drying experiments to improvetiter and process yield.
Design and execute stability studies and producttesting of formulation prototypes and commercial products.
Interpret resultsand design studiesfor process improvements using statistical Design of Experiments (DOE) methodology
Provides scientific technical support for technology transferof processes to manufacturing
Leads/Participates in various cross functional technology development teams.
Manage and motivate small team of researchers
Authors and contributes to scientific publications, patents, and regulatory submissions.
Effectively presentsresults at internalmeetings and externalscientific meetings.
PhD (or MSc with 3 yrs experience) in Microbiology, Fermentation, Bioengineering, Chemical Engineering, or related field.
Strong workingknowledge of basic microbiology and fermentation techniques (i.e., sterile technique, plating cells on agar plates, serial dilutions) is required.
Leadership experience important
Experience with aerobic and obligate anaerobic strain cultivation is important
Experience with live microbialformulation and stabilization processes is a plus.
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